Prof. Gian Maria Pacifici

PRESENT POSITION

I am in pension since November 1st 2014. My previous position was Professore Associato di Farmacologia (Italian equivalent of Associate Professor of Pharmacology), Medical School, University of Pisa, Pisa, Italy. I work at home, where I have a computer, a printer and a scanner and my work is very productive.

RESEARCH EXPERIENCE AND PAST AND PRESENT APPOINTMENTS

  • September 1971-April 1974: Research fellow at the Institute for Pharmacological Research Mario Negri (Laboratory of Clinical Pharmacology) Milan, Italy.
  • May 1974-May 1978: Different positions at the Department of General Pathology, Medical School, University of Pisa, Pisa, Italy.
  • September 1978-August 1979: Research Fellow at the Department of Clinical Pharmacology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.
  • September 1979-August 1980: Research Fellow at the Department of Clinical Pharmacology, at Karolinska Institutet, Huddinge University Hospital, Huddinge, Sweden.
  • September 1980-June 1983: In 1983, the applicant achieved the Ph.D. in Medical Sciences at the Karolinska Institute, Huddinge Hospital, Department of Clinical Pharmacology.
  • July-September 1981, 1982, 1983 and 1984: Research Fellow at the Department of Clinical Pharmacology, Karolinska Institutet, Huddinge Hospital, Huddinge, Sweden.
  • From June 1983-1984: Associate Professor of Pharmacology at the University of Pisa.
  • July-September 1985 and 1986: Fellow at the Division of Clinical Pharmacology, University Hospital, Uppsala, Sweden.
  • July-September 1987: Honour Research Fellow at the Department of Pharmacology and Therapeutics, University of Liverpool, UK.
  • July-August 1988: Fellow at the Unit of Clinical Pharmacology, Mayo Foundation, Rochester, Minnesota, USA.
  • August-September 1989: Fellow at the Unit of Clinical Pharmacology, Department of Clinical Pharmacology, Radcliffe Infirmary, Oxford, UK.
  • October 1993: Visiting Scientist at the Department of Pharmacology, Arizona University, Tucson (AZ, USA). The object of the visit was learning the techniques for slicing human tissues and the use of tissue slices in studies of drug metabolism.
  • January 1989-2004: Associate Professor of Pharmacology at the University of Pisa.
  • 2005-till present: At present, the main scientific interest of Gian Maria Pacifici is the study of the clinical pharmacology of drugs which are administered to neonates. In particular, he published three articles on the placental transfer of drugs in man.

MEMBERSHIPS OF PROFESSIONAL SOCIETY

  • Member of the European Society of Developmental and Pediatrics and prenatal Pharmacology (EDPP).

SCIENTIFIC INTERNATIONAL ORGANISATION ACTIVITIES

  • Member of the Editorial Board of the many international journals.
  • Italian delegate at the European Commission for the action “Predicting and managing variability in the kinetics and effects of drugs during their discovery, development and use” in the frame of Corporation in the Field of Scientific and Technical Research (Action COST B1).
  • Italian delegate at the European Commission for the action “Modelling in drug development” in the frame of Corporation in the Field of Scientific and Technical Research (Action COST B15).
  • Italian delegate at the European Commission for the action “Physiologically based Pharmaco-toxicokinetics and dynamics” in the frame of Corporation in the Field of Scientific and Technical Research (Action COST B25).
  • Councillor of the International Society for the Study of Xenobiotics (ISSX) for the period January 1990 to December 1993.
  • Member of the financial Committee of the International Society for the Study of Xenobiotics (ISSX) (from 1993 to 1998).
  • 1994-1997 Co-coordinator of the Concerted Action by the title: “Identification of early factors in the variability of drug metabolism in man” in the frame of Biomed project. Contract BMH1 CT94-1622 (European Commission, Brussels).
  • Co-editor with Dr. G.N. Fracchia of the book: “Advances in Drug Metabolism in Man” published by the European Commission. DG XII – Science, Research and Development (EUR 154139 EN – ISBN 92-827-3982-1; 1995). This book was considered a text book of drug metabolism in man and was freely distributed by the European Commission to all Departments of Pharmacology and Clinical Pharmacology to the five continents.
  • Co-editor with Prof. Olavi Pelkonen, Professor of Pharmacology, University of Oulu, Finland, of the book: “Interindividual Variability in Human Drug Metabolism”. Taylor & Francis, London, UK (2001; ISBN 0-7484-0864-9; 2001).
  • Co-editor with Prof. Michel Coughtrie, Division of Pathology and Neuroscience, Ninewells Hospital and Medical, University oF Dudeen, Dundee, Dundee, Scotland of the book: “Cytosolic Human Sulfotransferases”. Taylor & Francis-CRC, Boca Raton, FL, USA. (2005; ISBN 0-415-28462-7).
  • Member of the National Advisory Committee of the 7th World Conference on Clinical Pharmacology and Therapeutics (CPT2000).
  • Member of the National Advisory Committee of the 13th Symposium on Microsomes and drug oxidation (MDO2000).

LIST OF SCHOLARSHIPS RECEIVED

  • Institute Mario Negri for Pharmacological Research, Milan, Italy. Period.
  • The British Council, London, UK, period: 1978-1979).
  • The Stiftelsen Blanceflor Boncompagni-Ludovisi, Stockholm, Sweden.
  • The Karolinska Institutet, Stockholm, Sweden.
  • NATO, Rome.
  • The Swedish Medical Council, Stockholm.
  • The Nobel Foundation and The Nobel Medical Committee, Stockholm, Sweden.
  • The European Science Foundation, Strasbourg, France.
  • CNR (Rome, Italy) and The British Council, UK.

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