Prof. Chenghua Li

PRESENT POSITION

My research interest covers investigating the molecular interactions of pathogens Vibrio splendidus with their host Apostichopus japonicas, an economic cultured animal in China. In particular, our focus is on:

  • Investigating the role of microRNAs in marine invertebrate biology and host-pathogen interactions, in particular anti-bacterial responses.
  • Exploring bacterial encoded genes that are responsible for infection, pathogenesis and manipulation of host gene expression machinery.

Selected Publications（First author or Corresponding author only）

Before 2010：

  • Li C., Song L*., Zhao J., Zou H., Su J., Zhang H. Genomic organization, nucleotide sequence analysis of the core histone genes cluster in Chlamys farreri and molecular evolution assessment of the H2A and H2B. DNA Sequence. 2006; 17(6): 440-451.（IF=0.569）
  • Li C., Song L*., Zhao J., Zhu L., Zou H., Zhang H., Wang H., Cai Z. The preliminary study on a potential antibacterial peptide derived from histone H2A in hemocytes of scallop Chlamys farreri. Fish Shellfish Immunol. 2007, 22 (6): 663-672. （IF=3.160）
  • Li C., Zhao J., Song L*., Mu C., Zhang H., Gai Y., Qiu L., Yu Y., Ni D., Xing K. Molecular cloning, characterization, expression and functional analysis of an anti-lipopolysaccharide factor from Chinese mitten crab Eriocheir sinensis. Dev Comp Immunol. 2008, 32 (7):784-794. （IF=2.833）
  • Li C., Ni D., Song L*., Zhao J., Zhang H. Li L. Molecular cloning and characterization of a catalase from Zhikong scallop Chlamys farreri. Fish Shellfish Immunol. 2008, 24 (1): 27-34.（IF=3.160）
  • Li C*., Zhao J., Song L*. A review of advances in research on marine molluscan antimicrobial peptides and their potential application in aquaculture. Molluscan Res. 2009, 29(1):17-26.(Invited Review).（IF=0.583）

2010：

  • Zhao J., Li C*., Chen A., Li L., Su X., Li T. Molecular characterization of a novel big defensin from clam Venerupis philippinarum. PLoS One. 2010, 5(10):e13480.（IF=4.411）
  • Li C., Wang L., Ning X., Chen A., Zhang L., Qin S., Wu H., Zhao J*. Identification two small heat shock proteins with different response profile to environmental stresses in Venerupis philippinarum. Cell Stress Chaperon. 2010, 15(6): 897-904. （IF=3.162）
  • Zhao J., Qiu L., Ning X., Chen A., Wu H., Li C*. Cloning and characterization of an Invertebrate type lysozyme from Venerupis philippinarum. Comp Biochem Phys B 2010, 156: 56-60.（IF=1.989）
  • Li C*., Zhang H., Li L., Song L*. Identification of a cathepsin D potentially involved in H2A cleavage from scallop Chlamys farreri. Mol Biol Rep. 2010, 37(3): 1451-1460.（IF=1.875）
  • Li C., Qiu L., Ning X., Chen A., Qin S., Wu H., Zhao J*. The first molluscan TCTP in Venerupis philippinarum: molecular cloning and expression analysis. Fish Shellfish Immunol. 2010, 29(9): 530-533.（IF=3.044）
  • Li C., Sun H., Chen A., Ning X., Wu H., Qin S., Xue Q., Zhao J*. Identification and characterization of an intracellular Cu, Zn-superoxide dismutase (icCuZnSOD) gene from clam Venerupis philippinarum. Fish Shellfish Immunol. 2010, 28: 499-503. （IF=3.044）

2011：

  • Jin C., Li C*., Su X., Li T. Identification and characterization of a Tegillarca granosa ferritin regulated by iron ion exposure and thermal stress. Dev Comp Immunol. 2011, 35:745-751.（IF=3.268）
  • Li C*., He J., Su X., Li T. A manganese superoxide dismutases in blood clam Tegillarca granosa: molecular cloning, tissues distribution and expression analysis. Comp Biochem Phys B 2011, 159:64-70.（IF=1.923）
  • Li C., Li H., Su X., Li T*. Identification and characterization of a clam ferritin from Sinonovacula constricta. Fish Shellfish Immunol. 2011, 30:1147-1151.（IF=3.322）
  • Li C., Li L., Liu F., Ning X., Chen A., Zhang L., Wu H., Zhao J*. Alternation of Venerupis philippinarum Hsp40 gene expression in response to pathogen challenge and heavy metal exposure. Fish Shellfish Immunol. 2011, 30(1):447-450.（IF=3.322）
  • Zhang L., Zhao J., Li C*., Su X., Chen A., Li T., Qin S. Cloning and characterization of allograft inflammatory factor-1 (AIF-1) from manila clam Venerupis philippinarum. Fish Shellfish Immunol. 2011, 30(1): 148-153.（IF=3.322）
  • Li C*., Yu S., Zhao J., Su X., Li T. Cloning and characterization of a sialic acid binding lectins (SABL) from Manila clam Venerupis philippinarum. Fish Shellfish Immunol. 2011, 30:1202-1206.（IF=3.322）

2012：

  • Li C., Li Z., Li Y., Zhou J., Zhang C., Su X*., Li T. A ferritin from Dendrorhynchus zhejiangensis with heavy metals detoxification activity. Plos ONE. 2012, 7(12):e51428.（IF=3.73）
  • Li C*., Su X*., Li Y., Li T., Sun C., Zhou T., Liu H. Two classes of glutathione S-transferase genes with different response profiles to bacterial challenge in Venerupis philippinarum. Fish Shellfish Immunol. 2012, 32:219-222.（IF=2.964）
  • Li C*., Feng W., Qiu L., Xia C., Su X*., Jin C., Zou T., Zeng Y., Li T. Characterization of skin ulceration syndrome associated microRNAs in sea cucumber Apostichopus japonicus by deep sequencing. Fish Shellfish Immunol. 2012,33:436-441.（IF=2.964）
  • Li C., Ying Q., Su X*., Li T. Development and application of reverse transcription loop-mediated isothermal amplification for detecting live Shewanella putrefaciens in preserved fish sample. J Food Sci 2012, 77(4):M226-M230.（IF=1.775）
  • Li C*., Su X*., Wang M., Li Y., Li Y., Zhou J., Li T. Alteration of Phascolosoma esculenta heat shock protein 90 expression under heavy metal exposure and thermal stress. Genet Mol Res 2012,11 (3):2641-2651.（IF=0.994）

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