Prevalence and associated factors of hypertension in adults in Lubumbashi, Democratic Republic of the Congo: A hospital cross-sectional study
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Abstract
Introduction: Hypertension is the leading cause of morbidity and mortality from cardiovascular disease worldwide. Knowledge of its prevalence and associated factors helps to prevent its complications. The objectives of this study were to determine the prevalence and associated factors of hypertension in hospitals in Lubumbashi, Democratic Republic of the Congo.
Methods: A cross-sectional analytic study was conducted among 520 adults from February 6 to November 30, 2023 in 2 health facilities in the city of Lubumbashi (Afia Polyclinic - Don Bosco and Jason Sendwe Provincial General Reference Hospital). Participants were selected by systematic random sampling. Hypertension was defined when the subject had a blood pressure (BP) ≥ 135/85 mmHg on diurnal Ambulatory Blood Pressure Monitoring (ABPM) or ≥ 180/110 mmHg on clinic oscillometric BP measurement (OBPM), or when he/she had self-reported hypertension and/or was taking antihypertensive medication even if diurnal ABPM was normal. Factors associated with hypertension were determined using a logistic regression model at the 5% significance level.
Results: The prevalence of hypertension was 32.8% (95% CI: 28.9%-37.0%). Factors significantly associated with hypertension included age ≥50 years (AOR = 4.0 [1.2-12.7]), dyslipidemia (AOR = 18.6 [3.2-107.4]), hypercalcemia (AOR = 171.6 [32.5-905.9]), hyperkalemia (AOR = 27.6 [7.1-107.8]), and hypernatremia (AOR = 948.1 [160.0-5619.3]).
Conclusion: This study reveals the high hospital prevalence of hypertension and the factors associated with it, emphasizing the necessity for targeted interventions for at-risk populations, especially the elderly and those with electrolyte imbalances.
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References
- GBD 2017 Risk Factor Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet. 2018, 392(10159): 1923-1994. https://doi.org/10.1016/S0140-6736(18)32225-6
- Ataklte F, Erqou S, Kaptoge S. Global status report on noncommunicable diseases 2014. Geneva: World Health Organization [Internet], 2015. https://www.who.int/publications-detail-redirect/9789241564854
- Musung JM, Kakoma PK, Kaut Mukeng C, et al. Prevalence of Hypertension and Associated Factors in Lubumbashi City, Democratic Republic of Congo: A Community-Based Cross-Sectional Study. Corrao S, ed. International Journal of Hypertension. 2021, 2021: 1-8. https://doi.org/10.1155/2021/6674336
- Poulter NR, Prabhakaran D, Caulfield M. Hypertension. The Lancet. 2015, 386(9995): 801-812. https://doi.org/10.1016/s0140-6736(14)61468-9
- Bao W, Threefoot SA, Srinivasan SR, et al. Essential hypertension predicted by tracking of elevated blood pressure from childhood to adulthood: The Bogalusa heart study*. American Journal of Hypertension. 1995, 8(7): 657-665. https://doi.org/10.1016/0895-7061(95)00116-7
- Yang BY, Qian Z, Howard SW, et al. Global association between ambient air pollution and blood pressure: A systematic review and meta-analysis. Environmental Pollution. 2018, 235: 576-588. https://doi.org/10.1016/j.envpol.2018.01.001
- Ngombe LK, Cowgill K, Monga BB, et al. Prévalence de l’hypertension artérielle dans la population des meuniers de la ville de Lubumbashi, République Démocratique du Congo. Pan African Medical Journal. 2015, 22. https://doi.org/10.11604/pamj.2015.22.152.6677
- Shin S, Bai L, Oiamo TH, et al. Association Between Road Traffic Noise and Incidence of Diabetes Mellitus and Hypertension in Toronto, Canada: A Population‐Based Cohort Study. Journal of the American Heart Association. 2020, 9(6). https://doi.org/10.1161/jaha.119.013021
- Kreutz R, Dobrowolski P, Prejbisz A, et al. Lifestyle, psychological, socioeconomic and environmental factors and their impact on hypertension during the coronavirus disease 2019 pandemic. Journal of Hypertension. 2020, 39(6): 1077-1089. https://doi.org/10.1097/hjh.0000000000002770
- Umba EK, Ngoyi JM, Katanga LM, et al. Facteurs de risque associés à l’hypertension artérielle (HTA) chez les personnels soignants. Cas de l’Hôpital Gécamines Sud de Lubumbashi. Revue de l'Infirmier Congolais. 2020, 4(2): 31-35.
- Myers MG, Asmar R, Staessen JA. Office blood pressure measurement in the 21st century. The Journal of Clinical Hypertension. 2018, 20(7): 1104-1107. https://doi.org/10.1111/jch.13276
- Stergiou GS, Palatini P, Parati G, et al. 2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement. Journal of Hypertension. 2021, 39(7): 1293-1302. https://doi.org/10.1097/hjh.0000000000002843
- Mancia Chairperson G, Kreutz Co-Chair R, Brunström M, et L. 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension Endorsed by the European Renal Association (ERA) and the International Society of Hypertension (ISH). Journal Of Hypertension. 2023, 41(12): 1874-2071. https://doi.org/10.1097/HJH.0000000000003480
- Hodgkinson J, Mant J, Martin U, et al. Relative effectiveness of clinic and home blood pressure monitoring compared with ambulatory blood pressure monitoring in diagnosis of hypertension: systematic review. BMJ. 2011, 342. https://doi.org/10.1136/bmj.d3621
- Fernando N, Decio Mion J. What is the best way to measure blood pressure? Annals of Circulation. Published online March 20, 2021: 001-003. https://doi.org/10.17352/ac.000017
- Huang QF, Yang WY, Asayama K, et al. Ambulatory Blood Pressure Monitoring to Diagnose and Manage Hypertension. Hypertension. 2021, 77(2): 254-264. https://doi.org/10.1161/hypertensionaha.120.14591
- Groupe MBNEXT. Europe. laboratoires analyses médicales LIMS, Manuel de prélèvement prea-doc-027 version 05. 2021. https//.www.lims-mbnext.be
- OMS. International Classification of Adult Underweight, Overweight and Obesity According to BMI. 2024. https://apps.who.int/bmi
- Dinakis E, Nakai M, Gill P, et al. Association Between the Gut Microbiome and Their Metabolites With Human Blood Pressure Variability. Hypertension. 2022, 79(8): 1690-1701. https://doi.org/10.1161/hypertensionaha.122.19350
- Zeitouni M, Sabouret P, Kerneis M, et al. 2019 ESC/EAS Guidelines for management of dyslipidaemia: strengths and limitations. European Heart Journal - Cardiovascular Pharmacotherapy. 2020, 7(4): 324-333. https://doi.org/10.1093/ehjcvp/pvaa077
- Bassakouahou JM, Ikama MS, Mbolla BE, et al. Profil des patients admis pour hypertension dans le service de cardiologie et médecine interne du Centre Hospitalier et Universitaire de Brazzaville (Congo). Médecine d'Afrique Noire. 2015, 62(12): 599.
- Yaméogo AA, Tiendrebeogo H, Zabsonre P. Etude du profil épidémiologique, clinique et évolutif de l’hypertension artérielle en milieu hospitalier de Bobo-Dioulasso, 1997. https://dicames.online/jspui/handle/20.500.12177/2431
- Salam O, Zan AA, Ouedraogo EMW, et al. Profil de l’Hypertension Artérielle dans un Hôpital Régional au Burkina Faso. Health Sciences and Disease. 2021, 22(12). https://doi.org/10.5281/hsd.v22i12.3061
- Diallo AD, Ticolat R, Adom AH, et al. Étude de la mortalité et des facteurs de léthalité dans l’hypertension artérielle de l’adulte noir Africain. Médecine Afr. Noire. 1998, 45: 624-627.
- Damorou F, Baragou S, Pio M, et al. Morbidité et mortalité hospitalière des maladies cardiovasculaires en milieu tropical: exemple d’un centre hospitalier à Lomé (Togo). Pan African Medical Journal. 2014, 17. https://doi.org/10.11604/pamj.2014.17.62.2237
- Diallo BA. Profil épidémiologique de l’HTA en milieu hospitalier à Bamako. In Médecine d’Afrique Noire. 1994, 41(2). https://www.santetropicale.com/Resume/24107.pdf
- Damorou F, Togbossi E, Pessinaba S, et al. Epidemiology and diagnostic circumstances of arterial hypertension in the hospital environment in Kpalime (second largest city in Togo). Le Mali Medical. 2008, 23(4): 17-20.
- Patrick MT. Cardiopathie hypertensive à Lubumbashi: profil épidémiologique et clinique. Revue Africaine de Médecine et de Santé Publique. 2023, 4-5. http://rams-journal.com/index.php/RAMS/article/view/153
- Fondation de Recherche sur l’Hypertension Artérielle; Femme et Hypertension Artérielle 5 rue des Colonnes du Trône 75012 Paris. https://frhta.org/femmes-et-hypertension
- Longo M, Beya E, Ekwanzala, et al. Enquete Sur Les Facteurs De Risque Des Maladies Non Transmissibles A Kinshasa, Capitale De La Rd Congo Selon L’approche STEPS De L’OMS, Kinshasa, Novembre 2006. http://extranet.who.int
- Atoba BCR, Kyembe TC, Batina AS, et al. Prévalence,connaissance et degré de contrôle de l’hypertension artérielle à Kisangani, RD Congo. Kisangani Med. 2015, 5: 86-93. https://pesquisa.bvsalud.org/gim/resource/pt/afr-198293
- Katchunga PB, M’Buyamba-Kayamba JR, Masumbuko BE, et al. Hypertension artérielle chez l’adulte Congolais du Sud Kivu : résultats de l’étude Vitaraa. La Presse Médicale. 2011, 40(6): e315-e323. https://doi.org/10.1016/j.lpm.2010.10.036
- MP B, JR MK, NG N, et al. Trends in prevalence of obesity and hypertension in an urban Congolese community. Journal of Epidemiological Research. 2018, 4(1): 33. https://doi.org/10.5430/jer.v4n1p33
- Beaney T, Schutte AE, Tomaszewski M, et al. May Measurement Month 2017: an analysis of blood pressure screening results worldwide. Lancet Glob Health. 2018, 6(7): 736-743. https://doi.org/10.1016/S2214-109X(18)30259-6
- Corrigendum to: May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension. European Heart Journal. 2019, 40(37): 3109-3109. https://doi.org/10.1093/eurheartj/ehz373
- Abebe SM, Berhane Y, Worku A, et al. Prevalence and Associated Factors of Hypertension: A Crossectional Community Based Study in Northwest Ethiopia. Li Y, ed. PLOS ONE. 2015, 10(4): e0125210. https://doi.org/10.1371/journal.pone.0125210
- Roba HS, Beyene AS, Mengesha MM, et al. Prevalence of Hypertension and Associated Factors in Dire Dawa City, Eastern Ethiopia: A Community-Based Cross-Sectional Study. International Journal of Hypertension. 2019, 2019: 1-9. https://doi.org/10.1155/2019/9878437
- Khader Y, Batieha A, Jaddou H, et al. Hypertension in Jordan: Prevalence, Awareness, Control, and Its Associated Factors. International Journal of Hypertension. 2019, 2019: 1-8. https://doi.org/10.1155/2019/3210617
- Pinto E. Blood pressure and ageing. Postgraduate Medical Journal. 2007, 83(976): 109-114. https://doi.org/10.1136/pgmj.2006.048371
- Joly L, Perret-Guillaume C, Nzietchueng R, et al. Vieillissement artériel: déterminants et conséquences cliniques. MT Cardio. 2008, 4(3): 220-228. https://doi.org/10.1684/mtc.2008.0142
- Williams B, Mancia G. Ten Commandments of the 2018 ESC/ESH HTN Guidelines on Hypertension in Adults. European Heart Journal. 2018, 39(33): 3007-3008. https://doi.org/10.1093/eurheartj/ehy439
- Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report. Circulation. 2002, 106(25): 3143-3143. https://doi.org/10.1161/circ.106.25.3143
- Dabrowska E, Narkiewicz K. Hypertension and Dyslipidemia: the Two Partners in Endothelium-Related Crime. Current Atherosclerosis Reports. 2023, 25(9): 605-612. https://doi.org/10.1007/s11883-023-01132-z
- Affangla DA, Kane A, Akanni SC, et al. Aspects épidémiologiques de l’association hypertension artérielle et diabète de type 2 à l’hôpital Saint Jean de Dieu de Thiès (Sénégal). Rev Afr Médecine Interne. 2023, 10(1-2): 33-39.
- Lazreg Y, Boutaleb R, El Hebil M, et al. L’hypertension artérielle et risque cardiovasculaire en milieu hospitalier CHU Mohamed VI-Oujda. Néphrologie & Thérapeutique. 2016, 12(5): 401-402. https://doi.org/10.1016/j.nephro.2016.07.117
- Rucker AJ, Rudemiller NP, Crowley SD. Salt, Hypertension, and Immunity. Annual Review of Physiology. 2018, 80(1): 283-307. https://doi.org/10.1146/annurev-physiol-021317-121134
- Wilck N, Matus MG, Kearney SM, et al. Salt-responsive gut commensal modulates TH17 axis and disease. Nature. 2017, 551(7682): 585-589. https://doi.org/10.1038/nature24628
- La fédération française des diabétiques – Hypertension artérielle et diabète: une association fréquente. L’hypertension artérielle: une maladie très fréquente CFP-MFC – Ameli.fr – Le traitement des complications du diabète Revue Médicale de l’Assurance Maladie volume 34 n°2/avril-juin 2003 – Hypertension artérielle sévère : prise en charge des malades hypertendus et diabétiques en France. https://www.giphar.fr
- Société Française de Cardiologie. Cardio Online Chapitre 4 – Item 224: Hypertension Arterielle de l’Adulte et de l’Enfant Disponible sur. https://www.sfcardio.fr
- Carbone LD, Bush AJ, Barrow KD, et al. The relationship of sodium intake to calcium and sodium excretion and bone mineral density of the hip in postmenopausal African-American and Caucasian women. Journal of Bone and Mineral Metabolism. 2003, 21(6): 415-420. https://doi.org/10.1007/s00774-003-0437-3