Open Access Peer-reviewed Research Article

In Vivo Study of Gold-Nanoparticles Using Different Extracts for kidney, liver function and Photocatalytic Application

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Process for animal studies in albino rabbits
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Submitted   Mar 22, 2019
Published   Apr 12, 2019
Issue    Vol 1 No 1 (2019)
DOI   10.25082/CR.2019.01.004

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Muhammad Isa Khan
Department of Physics, Faculty of Science, University of Gujrat, Hafiz Hayat Campus, Gujrat, 50700, Pakistan。
Seemab Dildar
Department of Physics, Faculty of Science, University of Gujrat, Hafiz Hayat Campus, Gujrat, 50700, Pakistan； University of the Punjab, Physics Lahore, Pakistan.
Tahir Iqbal
Department of Physics, Faculty of Science, University of Gujrat, Hafiz Hayat Campus, Gujrat, 50700, Pakistan.
Muhammad Shakil
Department of Physics, Faculty of Science, University of Gujrat, Hafiz Hayat Campus, Gujrat, 50700, Pakistan.
Muhammad Bilal Tahir
Department of Physics, Faculty of Science, University of Gujrat, Hafiz Hayat Campus, Gujrat, 50700, Pakistan.
Muhammad Rafique
Department of Physics, Faculty of Science, University of Gujrat, Hafiz Hayat Campus, Gujrat, 50700, Pakistan.
Farooq Aziz
Department of Physics, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Sardar Bibi
Department of biotechnology, Virtual University, Pakistan.
Mohsin Ijaz corresponding author
Department of Physics, Faculty of Science, University of Gujrat, Hafiz Hayat Campus, Gujrat, 50700, Pakistan.

Abstract

We report novel gold nanoparticles by green method for different fruit extracts have gaining greater attention due to its versatile properties in different applications. In this article, GNPs synthesis is demonstrated successfully using fresh fruit extract of punica granatum and fragaria. The optical properties, morphology and elemental analysis of samples was done by using) different characterization techniques like SEM EDX and UV-Visible spectroscopy Biocompatibility of GNPs was determined by ALT, AST, ALP, Urea, Creatinine tests and also to investigate the effects of prepared GNPs on the kidney and liver functions. The GNPs prepared by fruit extract of punica granatum have more effects on the rabbits than GNPs prepared from fragaria but this effect normalizes after three days which shows its biocompatibility. To explore the photocatalytic activity of the GNPs the photocatalytic degradation of MB dye is also investigated. The results revealed that GNPs prepared through green synthesis route are found to be efficient enhancement in the degradation of MB dye in visible region due to large surface area. These particles were more active in catalytic reduction due to their high surface energy and in bio-medical applications as biocompatibility.

Keywords
green method, AuNPs, biocompatibility, photocatalytic activity

Article Details

How to Cite
Khan, M., Dildar, S., Iqbal, T., Shakil, M., Tahir, M., Rafique, M., Aziz, F., Bibi, S., & Ijaz, M. (2019). In Vivo Study of Gold-Nanoparticles Using Different Extracts for kidney, liver function and Photocatalytic Application. Chemical Reports, 1(1), 36-42. https://doi.org/10.25082/CR.2019.01.004
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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