Open Access Peer-reviewed Research Article

Acute renal failure as severe malaria complication in Lubumbashi: Management and follow-up in an under-equipped setting

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Description of 14 children with acute renal failure during malaria in Lubumbashi
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Submitted   Oct 12, 2020
Published   Nov 2, 2020
Issue    Vol 3 No 1 (2020)
DOI   10.25082/AGPM.2020.01.001

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Deddy C. Kalonji
Department of Pediatrics and Public Health, Faculty of Medicine, University of Kamina, Kamina, Democratic Republic of Congo
Lebrun N. Kembo
General Hospital Reference of Kamina, Kamina, Democratic Republic of Congo
Matthieu I. Ngombe
Department of Pediatrics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Stéphanie L. Ngimbi
Department of Pediatrics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Alex K. Lumande
Department of Pediatrics, Faculty of Medicine, University of Kabinda, Kabinda, Democratic Republic of Congo
Eva K. Bukasa
Department of Surgery, Faculty of Medicine, University of Likasi, Likasi, Democratic Republic of Congo
Patient N. Mudait
Department of Surgery, Faculty of Medicine, University of Likasi, Likasi, Democratic Republic of Congo
Olivier Mukuku corresponding author
Institut Supérieur des Techniques Médicales de Lubumbashi, Lubumbashi, Democratic Republic of Congo
Augustin M. Mutombo
Department of Pediatrics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Michel N. Kabamba
Department of Pediatrics and Public Health, Faculty of Medicine, University of Kamina, Kamina, Democratic Republic of Congo
André K. Mutombo
Department of Pediatrics, Faculty of Medicine, Official University of Mbuji-Mayi, Mbuji-Mayi, Democratic Republic of Congo
Stanislas O. Wembonyama
Department of Pediatrics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo
Oscar N. Luboya
Department of Pediatrics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

Abstract

Purpose Acute renal failure (ARF) or acute kidney injury (AKI) is one of the major criteria for the severity of malaria according to WHO. The objective was to determine the frequency as well as to evaluate the management and follow-up of ARF during malaria in children in Lubumbashi. Material and methods This is a descriptive cross-sectional study over 48 months (January 1st, 2016 to December 30th, 2019) carried out at the pediatric service of the University Clinics of Lubumbashi. All children with an ARF with a positive thick blood smear were included in the study. Data were analyzed with SPSS 19 software. Results During this period, 910 patients (49.1%) were admitted for malaria. Among them, 14 patients, i.e. an intra-hospital prevalence of 0.78%, of which 6 boys (42.9%) and 8 girls (57.1%) had ARF. The mean age is 7.9±3.5 years. The serum creatinine level was between 0.54 and 15.2 mg/dL with a mean of 5.7 mg/dL. Kidney dialysis was only effective in 3 patients (21.4%) and diuretics were given 100% in all children. The mean length of stay was 13.4±8.7 days (range: 1 day and 18 days). Mortality was 21.4%. Conclusion The present study shows that ARF in childhood malaria in Lubumbashi is infrequent but of high mortality in our environment with limited resources where care is lacking and monitoring difficult.

Keywords
renal failure, Malaria, children, Lubumbashi

Article Details

How to Cite
Kalonji, D., Kembo, L., Ngombe, M., Ngimbi, S., Lumande, A., Bukasa, E., Mudait, P., Mukuku, O., Mutombo, A., Kabamba, M., Mutombo, A., Wembonyama, S., & Luboya, O. (2020). Acute renal failure as severe malaria complication in Lubumbashi: Management and follow-up in an under-equipped setting. Advances in General Practice of Medicine, 3(1), 19-22. https://doi.org/10.25082/AGPM.2020.01.001
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