Open Access Peer-reviewed Perspective

Disease prevention strategies using vitamin D

Article Sidebar

Download PDF
Submitted   Jan 7, 2020
Published   Jan 7, 2020
Issue    Vol 2 No 2 (2019)
DOI   10.25082/AHB.2019.02.005

Views

2870

Downloads

1657

Citations

PlumX Metrics

Main Article Content

Sunil J. Wimalawansa corresponding author
Cardiometabolic & Endocrine Institute, North Brunswick, N.J., USA

Abstract

During the past 15 years, the biological and scientific knowledge of the pleiotropic properties of vitamin D and its metabolites has expanded beyond the well-understood effects of vitamin D in calcium homeostasis and skeletal health.  Many, recently published peer-reviewed articles clinical and epidemiological studies support multiple extra-skeletal beneficial effects of having adequate serum 25 hydroxy vitamin D [25(OH)D] concentrations.  However, this knowledge has not translated into clinical practice.  Consequently, thousands of people are developing (and existing disease are getting worse) vitamin D deficiency release and complications , otherwise could have been prevented.

Keywords
disease prevention, vitamin D

Article Details

How to Cite
Wimalawansa, S. (2020). Disease prevention strategies using vitamin D. Advances in Health and Behavior, 2(2), 96-100. https://doi.org/10.25082/AHB.2019.02.005
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

References

  1. Wimalawansa SJ. Vitamin D: Everything You Need to Know. ISBN: 978-955-9098-94-2, Homagama, Sri Lanka: Karunaratne & Sons, 2012. https://doi.org/10.4038/sjdem.v2i2.4776
  2. Wimalawansa SJ. Non-musculoskeletal benefits of vitamin D. The Journal of Steroid Biochemistry and Molecular Biology, 2018, 175: 60-81. https://doi.org/10.1016/j.jsbmb.2016.09.016
  3. Wahl DA, Cooper C, Ebeling PR, et al. A global representation of vitamin D status in healthy populations. Archives of Osteoporosis, 2012, 7(1): 155-172. https://doi.org/10.1007/s11657-012-0093-0
  4. Moukayed M and Grant WB. The roles of UVB and vitamin D in reducing risk of cancer incidence and mortality: A review of the epidemiology, clinical trials, and mechanisms. Reviews in Endocrine and Metabolic Disorders, 2017, 18(2): 167-182. https://doi.org/10.1007/s11154-017-9415-2
  5. Pludowski P, Holick MF, Grant WB, et al. Vitamin D supplementation guidelines. The Journal of Steroid Biochemistry and Molecular Biology, 2017: S0960076017300316. https://doi.org/10.1016/j.jsbmb.2017.01.021
  6. Grant WB, Wimalawansa SJ, Holick MF, et al. Emphasizing the health benefits of vitamin D for those with neurodevelopmental disorders and intellectual disabilities. Nutrients, 2015, 7(3): 1538-1564. https://doi.org/10.3390/nu7031538
  7. Wimalawansa SJ. Vitamin D adequacy and improvements of comorbidities in persons with intellectual developmental disabilities. Journal of Childhood & Developmental Disorders, 2016, 2(3): 22-33. https://doi.org/10.4172/2472-1786.100030
  8. Haq A, Wimalawansa SJ, Pludowski P, et al. Clinical practice guidelines for vitamin D in the United Arab Emirates. The Journal of Steroid Biochemistry and Molecular Biology, 2018, 175: 4-11. https://doi.org/10.1016/j.jsbmb.2016.09.021
  9. Mason C, Xiao L, Imayama I, et al. Vitamin D3 supplementation during weight loss: a double-blind randomized controlled trial. American Journal of Clinical Nutrition, 2014, 99(5): 1015-1025. https://doi.org/10.3945/ajcn.113.073734
  10. Dhaliwal R, Mikhail M, Feuerman M, et al. The vitamin d dose response in obesity. Endocrine Practice, 2014, 20(12): 1258-1264. https://doi.org/10.4158/EP13518.OR
  11. Knutsen KV, Madar AA, Lagerlov P, et al. Does vitamin D improve muscle strength in adults? A randomized, double-blind, placebo-controlled trial among ethnic minorities in Norway. The Journal of Clinical Endocrinology & Metabolism, 2014, 99(1): 194-202. https://doi.org/10.1210/jc.2013-2647
  12. Chaney A, Heckman MG, Diehl NN, et al. Effectiveness and Outcomes of Current Practice in Treating Vitamin D Deficiency in Patients Listed for Liver Transplantation. Endocrine Practice, 2015, 21(aop): 1-26. https://doi.org/10.4158/EP14416.OR
  13. Farahati J, Nagarajah J, Gilman E, et al. Ethnicity, Clothing Style, and Body Mass Index are Significant Predictors of Vitamin D Insufficiency in Germany. Endocrine Practice, 2015, 21(2): 122-127. https://doi.org/10.4158/EP14320.OR
  14. Nagarjunakonda S, Amalakanti S, Uppala V, et al. High Prevalence of Vitamin D Deficiency in Chronic Nonspecific Musculoskeletal Pain. Musculoskeletal Care, 2017, 15(2): 163-166. https://doi.org/10.1002/msc.1154
  15. Gupta AK, BrashearMMand Johnson WD. Prediabetes and prehypertension in healthy adults are associated with low vitamin D levels. Diabetes Care, 2011, 34(3): 658-660. https://doi.org/10.2337/dc10-1829
  16. Munger KL, Zhang SM, O’Reilly E, et al. Vitamin D intake and incidence of multiple sclerosis. Neurology, 2004, 62(1): 60-65. https://doi.org/10.1212/01.WNL.0000101723.79681.38
  17. Ritterhouse LL, Crowe SR, Niewold TB, et al. Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus. Annals of the Rheumatic Diseases, 2011, 70(9): 1569-1574. https://doi.org/10.1136/ard.2010.148494
  18. Merlino LA, Curtis J, Mikuls TR, et al. Vitamin D intake is inversely associated with rheumatoid arthritis: results from the IowaWomen’s Health Study. Arthritis & Rheumatology, 2004, 50(1): 72-77. https://doi.org/10.1002/art.11434
  19. Feskanich D, Willett WC and Colditz GA. Calcium, vitamin D, milk consumption, and hip fractures: a prospective study among postmenopausal women. American Journal of Clinical Nutrition, 2003, 77(2): 504-511. https://doi.org/10.1093/ajcn/77.2.504
  20. Meier C, Woitge HW, Witte K, et al. Supplementation with oral vitamin D3 and calcium during winter prevents seasonal bone loss: a randomized controlled open-label prospective trial. Journal of Bone and Mineral Research, 2004, 19(8): 1221-1230. https://doi.org/10.1359/JBMR.040511
  21. McCullough ML, Robertson AS, Rodriguez C, et al. Calcium, vitamin D, dairy products, and risk of colorectal cancer in the Cancer Prevention Study II Nutrition Cohort (United States). Cancer Causes Control, 2003, 14(1): 1-12. https://doi.org/10.1023/A:1022591007673
  22. Tretli S, Schwartz GG, Torjesen PA, et al. Serum levels of 25-hydroxyvitamin D and survival in Norwegian patients with cancer of breast, colon, lung, and lymphoma: a population-based study. Cancer Causes Control, 2012, 23(2): 363-370. https://doi.org/10.1007/s10552-011-9885-6
  23. Garland CF, Kim JJ, Mohr SB, et al. Meta-analysis of allcause mortality according to serum 25-hydroxyvitamin D. American Journal of Public Health, 2014, 104(8): e43-50. https://doi.org/10.2105/AJPH.2014.302034
  24. Grober U and Holick MF. Diabetes prevention: Vitamin D supplementation may not provide any protection if there is no evidence of deficiency! Nutrients, 2019, 11(11): 2651. https://doi.org/10.3390/nu11112651
  25. Wimalawansa SJ. Associations of vitamin D with insulin resistance, obesity, type 2 diabetes, and metabolic syndrome. The Journal of Steroid Biochemistry and Molecular Biology, 2018, 175: 177-189. https://doi.org/10.1016/j.jsbmb.2016.09.017
  26. Wimalawansa SJ. Significance of plasma PTH-rp in patients with hypercalcemia of malignancy treated with bisphosphonate. Cancer, 1994, 73(8): 2223-2230. https://doi.org/10.1002/1097-0142(19940415)73:8h2223::AID-CNCR2820730831i3.0.CO;2-C
  27. Cooper C, Li H and Wimalawansa SJ. Cancer-associated hypercalcemia and parathyroid hormone-related peptide: a new peptide with diverse roles. Reg. Peptide Letters, 1997, 7: 39-42.
  28. Wimalawansa SJ, Razzaque DMS and Al-Daghri NM. Calcium and Vitamin D in Human Health: Hype or Real? The Journal of Steroid Biochemistry and Molecular Biology, 2017, 180: 4-14. https://doi.org/10.1016/j.jsbmb.2017.12.009
  29. Perez-Barrios C, Hernandez-Alvarez E, Blanco-Navarro I, et al. Prevalence of hypercalcemia related to hypervitaminosis D in clinical practice. Clinical Nutrition, 2016, 35(6): 1354-1358. https://doi.org/10.1016/j.clnu.2016.02.017
  30. Jones G. Pharmacokinetics of vitamin D toxicity. American Journal of Clinical Nutrition, 2008, 88(2): 582-586. https://doi.org/10.1093/ajcn/88.2.582S
  31. Scragg R, Waayer D, Stewart A, et al. The Vitamin D Assessment (ViDA) Study: design of a randomized controlled trial of vitamin D supplementation for the prevention of cardiovascular disease, acute respiratory infection, falls and non-vertebral fractures. Journal of Steroid Biochemistry & Molecular Biology, 2016, 164: 318-325. https://doi.org/10.1016/j.jsbmb.2015.09.010
  32. Manson JAE, Cook NR, Lee IM, et al. Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease. New England Journal of Medicine, 2019, 380(1): 33- 44. https://doi.org/10.1056/NEJMoa1809944
  33. Wimalawansa SJ. IOM recommendations vs. vitamin D guidelines applicable to the rest of the world[C]//5th International Conference on Vitamin D. 2017: 9.